Submitted by jec3011 on May 9, 2023 - 12:28pm
| Title | Macromolecular crowding meets tissue engineering by self-assembly: a paradigm shift in regenerative medicine. |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Satyam A, Kumar P, Fan X, Gorelov A, Rochev Y, Joshi L, Peinado H, Lyden D, Thomas B, Rodriguez B, Raghunath M, Pandit A, Zeugolis D |
| Journal | Adv Mater |
| Volume | 26 |
| Issue | 19 |
| Pagination | 3024-34 |
| Date Published | 2014 May 21 |
| ISSN | 1521-4095 |
| Keywords | Acrylic Resins, Cell Line, Collagen, Dextran Sulfate, Extracellular Matrix, Fibroblasts, Humans, Macromolecular Substances, Matrix Metalloproteinase 2, Regenerative Medicine, Tissue Engineering |
| Abstract | MMC, the addition of inert polydispersed macromolecules in the culture media, effectively emulates the dense in vivo extracellular space, resulting in amplified deposition of ECM in vitro and subsequent production of cohesive, ECM-rich living substitutes. |
| DOI | 10.1002/adma.201304428 |
| Alternate Journal | Adv Mater |
| PubMed ID | 24505025 |