Chapter 11. The role of bone marrow-derived cells in tumor angiogenesis and metastatic progression.

TitleChapter 11. The role of bone marrow-derived cells in tumor angiogenesis and metastatic progression.
Publication TypeJournal Article
Year of Publication2008
AuthorsPapaspyridonos M, Lyden D
JournalMethods Enzymol
Volume444
Pagination255-69
Date Published2008
ISSN1557-7988
KeywordsAnimals, Bone Marrow Cells, Cell Differentiation, Cell Movement, Chemokine CXCL12, Disease Progression, Humans, Neoplasm Metastasis, Neoplasms, Neovascularization, Pathologic, Receptors, CXCR4, Receptors, Vascular Endothelial Growth Factor, Signal Transduction
Abstract

Tumor angiogenesis is orchestrated by a complex set of secreted factors and collaboration between many different cell types. This chapter discusses the role of tumor-secreted angiogenic factors that are responsible for the recruitment of bone marrow-derived cells (BMDCs) at tumor sites and their role in tumor angiogenesis and progression.

DOI10.1016/S0076-6879(08)02811-5
Alternate JournalMethods Enzymol
PubMed ID19007668