Publications

Satyam A, Kumar P, Fan X, Gorelov A, Rochev Y, Joshi L, Peinado H, Lyden D, Thomas B, Rodriguez B et al..  2014.  Macromolecular crowding meets tissue engineering by self-assembly: a paradigm shift in regenerative medicine.. Adv Mater. 26(19):3024-34.

Huang Y, Hoffman C, Rajappa P, Kim J-H, Hu W, Huse J, Tang Z, Li X, Weksler B, Bromberg J et al..  2014.  Oligodendrocyte progenitor cells promote neovascularization in glioma by disrupting the blood-brain barrier.. Cancer Res. 74(4):1011-21.

Barcellos-Hoff MHelen, Lyden D, Wang TC.  2013.  The evolution of the cancer niche during multistage carcinogenesis.. Nat Rev Cancer. 13(7):511-8.

Chang Q, Bournazou E, Sansone P, Berishaj M, Gao SPaul, Daly L, Wels J, Theilen T, Granitto S, Zhang X et al..  2013.  The IL-6/JAK/Stat3 feed-forward loop drives tumorigenesis and metastasis.. Neoplasia. 15(7):848-62.

Kim J-H, Huse JT, Huang Y, Lyden D, Greenfield JP.  2013.  Molecular diagnostics in paediatric glial tumours.. Lancet Oncol. 14(1):e19-27.

Zhu H, Guariglia S, Yu RYL, Li W, Brancho D, Peinado H, Lyden D, Salzer J, Bennett C, Chow C-W.  2013.  Mutation of SIMPLE in Charcot-Marie-Tooth 1C alters production of exosomes.. Mol Biol Cell. 24(11):1619-37,S1-3.

Ghajar CM, Peinado H, Mori H, Matei IR, Evason KJ, Brazier H, Almeida D, Koller A, Hajjar KA, Stainier DYR et al..  2013.  The perivascular niche regulates breast tumour dormancy.. Nat Cell Biol. 15(7):807-17.

Brabletz T, Lyden D, Steeg PS, Werb Z.  2013.  Roadblocks to translational advances on metastasis research.. Nat Med. 19(9):1104-9.

Peinado H, Alečković M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, García-Santos G, Ghajar C et al..  2012.  Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.. Nat Med. 18(6):883-91.

Couto JPinto, Daly L, Almeida A, Knauf JA, Fagin JA, Sobrinho-Simões M, Lima J, Máximo V, Soares P, Lyden D et al..  2012.  STAT3 negatively regulates thyroid tumorigenesis.. Proc Natl Acad Sci U S A. 109(35):E2361-70.

Polkinghorn WR, Dunkel IJ, Souweidane MM, Khakoo Y, Lyden DC, Gilheeney SW, Becher OJ, Budnick AS, Wolden SL.  2011.  Disease control and ototoxicity using intensity-modulated radiation therapy tumor-bed boost for medulloblastoma.. Int J Radiat Oncol Biol Phys. 81(3):e15-20.

Acharya SS, Kaplan RN, Macdonald D, Fabiyi OT, DiMichele D, Lyden D.  2011.  Neoangiogenesis contributes to the development of hemophilic synovitis.. Blood. 117(8):2484-93.

Glazer PM, Grandis J, Powell SN, J Brown M, Helleday T, Bristow R, Powis G, Hill RP, Le Q-T, Pelroy R et al..  2011.  Radiation Resistance in Cancer Therapy: meeting summary and research opportunities. Report of an NCI Workshop held September 1-3, 2010.. Radiat Res. 176(3):e0016-21.

Peinado H, Lavotshkin S, Lyden D.  2011.  The secreted factors responsible for pre-metastatic niche formation: old sayings and new thoughts.. Semin Cancer Biol. 21(2):139-46.

Azare J, Doane A, Leslie K, Chang Q, Berishaj M, Nnoli J, Mark K, Al-Ahmadie H, Gerald W, Hassimi M et al..  2011.  Stat3 mediates expression of autotaxin in breast cancer.. PLoS One. 6(11):e27851.

Matei I, Ghajar CM, Lyden D.  2011.  A TeNaCious foundation for the metastatic niche.. Cancer Cell. 20(2):139-41.

James D, Nam H-song, Seandel M, Nolan D, Janovitz T, Tomishima M, Studer L, Lee G, Lyden D, Benezra R et al..  2010.  Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFbeta inhibition is Id1 dependent.. Nat Biotechnol. 28(2):161-6.

Ding B-S, Nolan DJ, Butler JM, James D, Babazadeh AO, Rosenwaks Z, Mittal V, Kobayashi H, Shido K, Lyden D et al..  2010.  Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration.. Nature. 468(7321):310-5.

Dunkel IJ, Khakoo Y, Kernan NA, Gershon T, Gilheeney S, Lyden DC, Wolden SL, Orjuela M, Gardner SL, Abramson DH.  2010.  Intensive multimodality therapy for patients with stage 4a metastatic retinoblastoma.. Pediatr Blood Cancer. 55(1):55-9.

Greenfield JP, Cobb WS, Lyden D.  2010.  Resisting arrest: a switch from angiogenesis to vasculogenesis in recurrent malignant gliomas.. J Clin Invest. 120(3):663-7.

Teo EH, Cross KJ, Bomsztyk ED, Lyden DC, Spector JA.  2009.  Gene therapy in skin: choosing the optimal viral vector.. Ann Plast Surg. 62(5):576-80.

Chan AS, Jensen KK, Skokos D, Doty S, Lederman HK, Kaplan RN, Rafii S, Rivella S, Lyden D.  2009.  Id1 represses osteoclast-dependent transcription and affects bone formation and hematopoiesis.. PLoS One. 4(11):e7955.

Psaila B, Lyden D.  2009.  The metastatic niche: adapting the foreign soil.. Nat Rev Cancer. 9(4):285-93.

Cross KJ, Bomsztyk ED, Weinstein AL, Teo EH, Spector JA, Lyden DC.  2009.  A novel method for targeted gene therapy in ischemic tissues through viral transfection of an expression cassette containing multiple repetitions of hypoxia response element.. Plast Reconstr Surg. 123(2 Suppl):76S-82S.

Rafii S, Lyden D.  2008.  Cancer. A few to flip the angiogenic switch.. Science. 319(5860):163-4.