Publications

Seandel M, Butler J, Lyden D, Rafii S.  2008.  A catalytic role for proangiogenic marrow-derived cells in tumor neovascularization.. Cancer Cell. 13(3):181-3.

Shmelkov SV, Butler JM, Hooper AT, Hormigo A, Kushner J, Milde T, St Clair R, Baljevic M, White I, Jin DK et al..  2008.  CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors.. J Clin Invest. 118(6):2111-20.

Papaspyridonos M, Lyden D.  2008.  Chapter 11. The role of bone marrow-derived cells in tumor angiogenesis and metastatic progression.. Methods Enzymol. 444:255-69.

Kerbel RS, Benezra R, Lyden DC, Hattori K, Heissig B, Nolan DJ, Mittal V, Shaked Y, Dias S, Bertolini F et al..  2008.  Endothelial progenitor cells are cellular hubs essential for neoangiogenesis of certain aggressive adenocarcinomas and metastatic transition but not adenomas.. Proc Natl Acad Sci U S A. 105(34):E54;authorreplyE55.

Peinado H, Rafii S, Lyden D.  2008.  Inflammation joins the "niche".. Cancer Cell. 14(5):347-9.

Wels J, Kaplan RN, Rafii S, Lyden D.  2008.  Migratory neighbors and distant invaders: tumor-associated niche cells.. Genes Dev. 22(5):559-74.

Rafii DC, Psaila B, Butler J, Jin DK, Lyden D.  2008.  Regulation of vasculogenesis by platelet-mediated recruitment of bone marrow-derived cells.. Arterioscler Thromb Vasc Biol. 28(2):217-22.

Kaplan RN, Psaila B, Lyden D.  2007.  Niche-to-niche migration of bone-marrow-derived cells.. Trends Mol Med. 13(2):72-81.

Dunkel IJ, Lee TC, Shi W, Beaverson KL, Novetsky D, Lyden D, Finlay JL, McCormick B, Abramson DH.  2007.  A phase II trial of carboplatin for intraocular retinoblastoma.. Pediatr Blood Cancer. 49(5):643-8.

Gilheeney SW, Lyden DC, Sgouros S, Antunes N, Gerald W, Kramer K, Lis E, Meyers P, Rosen N, Thaler HT et al..  2007.  A phase II trial of thalidomide and cyclophosphamide in patients with recurrent or refractory pediatric malignancies.. Pediatr Blood Cancer. 49(3):261-5.

Kaplan RN, Psaila B, Lyden D.  2006.  Bone marrow cells in the 'pre-metastatic niche': within bone and beyond.. Cancer Metastasis Rev. 25(4):521-9.

Jin DK, Shido K, Kopp H-G, Petit I, Shmelkov SV, Young LM, Hooper AT, Amano H, Avecilla ST, Heissig B et al..  2006.  Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes.. Nat Med. 12(5):557-67.

Kaplan RN, Rafii S, Lyden D.  2006.  Preparing the "soil": the premetastatic niche.. Cancer Res. 66(23):11089-93.

Psaila B, Kaplan RN, Port ER, Lyden D.  2006.  Priming the 'soil' for breast cancer metastasis: the pre-metastatic niche.. Breast Dis. 26:65-74.

Rafii S, Lyden D.  2006.  S100 chemokines mediate bookmarking of premetastatic niches.. Nat Cell Biol. 8(12):1321-3.

Karajannis MA, Lyden DC, Khakoo Y, Dunkel IJ.  2006.  Treatment-related myelodysplastic syndrome after chemotherapy for childhood low-grade astrocytoma.. J Pediatr Hematol Oncol. 28(10):700.

Shmelkov SV, St Clair R, Lyden D, Rafii S.  2005.  AC133/CD133/Prominin-1.. Int J Biochem Cell Biol. 37(4):715-9.

Vidal A, Zacharoulis S, Guo W, Shaffer D, Giancotti F, Bramley AH, de la Hoz C, Jensen KK, Kato D, MacDonald DD et al..  2005.  p130Rb2 and p27kip1 cooperate to control mobilization of angiogenic progenitors from the bone marrow.. Proc Natl Acad Sci U S A. 102(19):6890-5.

Kaplan RN, Riba RD, Zacharoulis S, Bramley AH, Vincent L, Costa C, MacDonald DD, Jin DK, Shido K, Kerns SA et al..  2005.  VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche.. Nature. 438(7069):820-7.

Avecilla ST, Hattori K, Heissig B, Tejada R, Liao F, Shido K, Jin DK, Dias S, Zhang F, Hartman TE et al..  2004.  Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis.. Nat Med. 10(1):64-71.

Wolden SL, Dunkel IJ, Souweidane MM, Happersett L, Khakoo Y, Schupak K, Lyden D, Leibel SA.  2003.  Patterns of failure using a conformal radiation therapy tumor bed boost for medulloblastoma.. J Clin Oncol. 21(16):3079-83.

Begemann M, Lyden D, Rosenblum MK, Lis E, Wolden S, Antunes NL, Dunkel IJ.  2003.  Primary leptomeningeal primitive neuroectodermal tumor.. J Neurooncol. 63(3):299-303.

Rafii S, Lyden D.  2003.  Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration.. Nat Med. 9(6):702-12.

Rafii S, Meeus S, Dias S, Hattori K, Heissig B, Shmelkov S, Rafii D, Lyden D.  2002.  Contribution of marrow-derived progenitors to vascular and cardiac regeneration.. Semin Cell Dev Biol. 13(1):61-7.

Heath JA, Broxson EH, Dole MG, Filippa DA, George D, Lyden D, Dunkel IJ.  2002.  Epstein-Barr virus-associated lymphoma in a child undergoing an autologous stem cell rescue.. J Pediatr Hematol Oncol. 24(2):160-3.